Oh, of course you also need to configure the buttons to their V5 actions as mentioned somewhere above. I don’t know what kind of the mystical “wiring layout” you are using, but you need to set up at least 24 virtual switches by entering 24 times (if it is empty or unused yet) -1 separated by commas into the switch pin configuration (appears for “Custom” or the “Mcp23017 …” layouts. Then you can select the “V5” profile and the configuration for the 20 switches of V5 should appear below. Apply/restart.