Thanks, for the comments.
Yes, I’m using the same jack settings in both environments (same period, buffer size and sample rate).
And yes, I’m testing with the same patches.
Finally I had some time to do another test.
I was able to get an I2S DAC (a suptronics x400 based on a PCM5122) and as I expected the performance is better, I don’t have xruns with NoiseMak3r but there are xruns with Obxd.
The last test that I can do is to change the SD Card, I didn’t check if swap is enabled in the ZynthianOS image but that could be the issue.
Would be great if someone with a similar build (Raspi 3b+ and Usb interface) could confirm that Zynthian image works without xruns when using OBxd and NoiseMak3r with Jalv.
Thanks