Hi @jollyDodger ,
I can answer some questions.
About USB hosting as OTG I reported in this contribution - Zynthian from scratch made by ToFFmashines - #12 by ToFF I use BomeBox for routing midi devices, more in the same thread.
Blokas Midihub conected on USB 2 port is recognized without problems by Zynthian. Of course only USB midi ports.
In remapig and midi chains on Zynthian I’m not very experienced, but last two points they seem feasible to me.
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